Efek Antiplasmodium Ekstrak Kulit Batang Asam Kandis (Garcinia parvifolia Miq) yang Diberikan Secara Intraperitoneal pada Mencit yang Diinfeksi dengan Plasmodium yoelii
Abstract: This study is trying
to assess the effect of the stem bark extract of Garcinia parvifolia Miq on
Plasmodium yoelii infected mice. Thirty mice, all male, were inoculated by
Plasmodium yoelii. They were randomly
allocated into 6 groups of 5 mice and each
group was treated with G. parvifolia¢s extract of 100 mg/kgBW/day, 300
mg/kgBW/day, 500 mg/kgBW/day and 1000 mg/kgBW/day respectively. Each groups was treated for the periode of 4
days after inoculation of P. yoelii. The
degree of parasitemia were examined daily using thin blood smears up to 4 days
from the inoculation and were analyzed by log-probit method. The results showed
that the ethanol extract displayed ED50 value less than 100 mg/kgBB/day.
Penulis: Tri Handayani, Susan
Marlina, Rita Marleta Dewi
Kode Jurnal: jpkedokterandd080027
