Contrast Induced Nephropathy
Abstrak: Incidens of contrast
induced nephropathy (CIN) ranging from 0 to 100% in retrospective cohort
studies depend on its definition, method of investigation and subject
characterization. In National Cardiovasculars Center Harapan Kita, CIN
incidence after percutaneous coronary intervention was 25% using definition of
0.5 mg/dl increase of serum creatinine. Clinical spectrum of CIN is widely
variably from only creatinine serum increment to acute renal failure. Pathogenesis
of CIN is related to hemodynamic compromize of renal blood flow and direct
toxic effect of contrast media. Some factors were identified as CIN risk
factors such as previous renal status, diabetes mellitus, hidration status,
contrast volume and osmality. Score system has been developed to predict CIN risk
after percutaneous coronary intervention. The Society of Cardiovascular
Angiography and Intervention (SCAI) proposed guideline to prevent CIN after
percutaneous coronary interventions.
Penulis: Nurul R Ningrum, Yoga
Yuniadi
Kode Jurnal: jpkedokterandd090028
