OPTIMALISASI FORMULA DAN GAYA TEKAN TERHADAP TEKSTURDAN KELARUTAN TABLET EFFERVESCEN BUAH MARKISA
ABSTRACT: The aims of this
research were to determine influences of formula andcompression force on
characteristic effervescent tablet of passion fruits. The researchwith
treatment variation of six formula and five compression force. Variations of
formulawere carried on by combining different ratio of citric acid and sodium
bicarbonate (1:3,1:2, 1:1, 3:1, 2:1, and 2:3 w/w) and compression force of
1000, 2000, 3000, 4000, and5000 N. Characteristic of effervescent tablet of
passion fruits that evaluated are textureand dissolution rate.The results of
research showed that the compression force significantlyinfluenced (α >
0.05) on the texture and dissolution rate of effervescent tablet. Variationsof
formula none significantly influenced (α < 0.05) on the texture and dissolution
rate.The effervescent tablet of passion fruits of good characteristic is
formula of ratio citricacid and sodium bicarbonate 1:2 w/w with compression
force 3000 N.
Keywords: formula, compression
force, effervescent tablet
Penulis: Ansar
Kode Jurnal: jppertaniandd110015
