ABSTRACT: Rhizhophora mucronata
is commonly found mangrove plant due to it’s wide distribution. The bark of
this plant used for traditional medicine as slimming, antidiarrhea ,
anticonstipation. The chemical compounds of R. mucronata are tannins,
alcaloide, flavanoids and saponin. In order to find out the effect of chemical
activity of this plant, a research entitled Fractionation Metanol Extracts Bark
of R. Mucronata and Inhibiting Capacity Assay against Escherichia coli Bacteria
has been carried out. The bark of R. mucronata was extracted by soxhlet with
methanol solvent. Than methanol extract was fractionated with developing
solvent kloroform : metanol (1:9) and producing five fractions that gave
positive result on test for alcaloide compounds. The result of infrared
spectroscopy that fraction 1-5 also contains of alcaloide. All fractions from
coulomn chromatography tested on E. coli with dilution method which gave result
that these fractions inhibit the growth of E. coli.
Key words: R. mucronata,
fraction, E. coli
Penulis: Dian Riana Ningsih,
Warsinah dan Suwandri
Kode Jurnal: jpkimiadd060024
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