The Influence of Hyperglycemia at Admission on In-hospital Arrhythmia Patients with Acute Coronary Syndrome
ABSTRACT: to determine the
incidence of in-hospital arrhythmias in patients with acute coronary syndrome
(ACS) and to determine the influence of hyperglycemia at admission (HA) on
in-hospital arrhythmias complicating ACS. Methods: a retrospective cohort study
was conducted using secondary data from medical records of patients with ACS
who were admitted to ICCU RSCM, between January 1st-December 31st, 2014.
Hyperglycemia at admission was defned when the blood glucose level at admission
was >140 mg/dL. The in-hospital arrhythmias encompassed atrial arrhythmia,
supraventricular tacchycardia (SVT), high grade AV block (HAVB), and
ventricular arrhythmia, during the frst seven days of hospitalization. Results:
there were 232 subjects in this study. The prevalence of HA was 50.43%. The
incidence of in-hospital arrhythmia was 21.55% (95% CI 16.26-26.84). In
bivariate analysis, there was signifcant association between HA and in-hospital
arrhythmia (RR 1.75; 95% CI 1.04-2.93). There were no association between type
of ACS, diabetes mellitus (DM), obesity, and hypertension, with the in-hospital
arrhythmias. In multivariate analysis, the adjusted OR of HA was 2.85 (95% CI
1.35-6.02), and DM was the confounding variable. Conclusion: the incidence of
in-hospital arrhythmias in patients with ACS was 21.55% (95% CI 16.26-26.84).
Hyperglycemia at admission may increase the risk of in-hospital arrhythmia in
patients with ACS.
Author: Ahmad Fariz M.Z. Zein,
Sally A. Nasution, Dyah Purnamasari, Arif Mansjoer
Journal Code: jpkedokterangg150238