UJI EFEK HIPOGLIKEMIK PEMBERIAN GABUNGAN INFUSA DAUN MAJA (Aegle marmelos CORREA) DAN DAUN MAHKOTA DEWA (PHALERIA MACROCARPA SCHEFF)PADA MENCIT JANTAN (MUS MUSCULUS)
Abstrak: The research on
hypoglicemic effect test of combination administrasion infusion of the Maja
leaves (Aegle marmelos Correa) and the Crown of God leaves (Phaleria macrocarpa
Scheff) on the blood glucose level of mice (Mus musculus) has been done. The
aim the research to know on hypoglicemic effect that has been given of
combination infusion from the both plants, basicly of scientific data. In
experiment 15 mice where divided in to 5 groups, each group consisted of 3
mice. The 1st group was given 1% w/v of Natrium CMC as a negative control, the
2nd group was given the crown of God leaves infusion 20% w/v, the 3rd group was
given the maja leaves infusion 15% w/v, the 4th group given the combination
administrasion infusion of the crown of God leaves and maja leaves and the 5th
group was given the glibenclamide suspension 0,002% w/v as a positive control.
The initial blood glucose level was measured 1 hour after the treatment was
given every hour in 5 hours after the infuse administrasion. The result of the
research showed that given of combination infusion of the Maja leaves (Aegle
marmelos Correa) and the Crown of God leaves (Phaleria macrocarpa Scheff) was
not significantly from the 0,002% w/v glibenclamide suspension as a positive
control but it has hypoglycemic effect at the 5th hours.
KATA KUNCI: Hypoglicemic;
Aegle marmelos Correa; Phaleria macrocarpa Scheff
Penulis: Nurshalati Tahar
Kode Jurnal: jpfarmasidd130413