UJI EFEK EKSTRAK ETANOL DAUN CINCAU HIJAU (Cyclea barbata Miers) SEBAGAI ANTIINFLAMASI PADA TIKUS PUTIH YANG DIINDUKSI KARAGEN
Abstrak: Inflammatory
medication which is commonly used is the treatment synthetically or
traditionally from the natural ingredients, the green grass jelly leaves
(Cyclea barbata Miers). This research aimed to determine the effects and the
most effective dose of the ethanol extract of green grass jelly leaves as an
anti-inflammatory in white rats induced by carrageenan. This research used 15
mice divide into 5 group. Group I (negative control) was given Na.CMC; group II
(positive control) was given Na.Diclofenac; group III, IV and V were given
ethanol extract of green grass jelly leaves (EEDCH) at the dose of 1.875
mg/kgBW, 3.75 mg/kgBW, and 7.5 mg/kgBW. Pretreatment on animals induced by
carrageenan 1% amounted to 0.1 mL in sub plantar on the soles of the mice. The measurements
were made every 1 hour for 5 hour by using the pletismometer tool. The result
showed that the ethanol extract of green grass jelly leaves has a potential as
anti-inflammatory. Based on the result
of statistical analysis of the one way ANOVA followed by Post Hoc Test
LSD showed that substance EEDCH at the dose of 7.5 mg/kgBW has
anti-inflammatory effect were not significantly different from the positive
control (Na.Diclofenac).
Keywords: Green grass jelly
leaves (Cyclea barbata Miers), anti-inflammatory, Na.Diclofenac
Penulis: Irma Santi, Bayu
Putra, Sri Wahyuni
Kode Jurnal: jpfarmasidd170400
