Toksisitas Akut dan Subkronis Ramuan Ekstrak Kelor dan Klabet sebagai Pelancar ASI dan Penambah Gizi
Abstract: Insufficient breast
milk intake from a mother to their babies may cause a poor infant growth. We
have conducted a research on mixture of klabet seed extracts (Trigonella
foenum-graecum L.) and kelor leaf extract (Moringa oleifera Lamk.) (1:1) for
increasing breast milk production in nursing mothers and nutritional supplement
for infants. The study is a completely randomized design. We used white rats
(Rattus novergicus), Wistar strain, as many as 50, that were divided into 5
dose groups for the acute toxicity testing and 40 rats in 4 dose groups for the
sub-chronic toxicity testing.The acute toxicity testing of fenugreek seed
extracts and moringa leaf extracts (1:1) results in a pseudo value LD50
>4,000 mg/200g bw, therefore we classified the materials to practically
non-toxic (PNT). For the subchronic toxicity testing, the result showed a
normal state on liver and kidney function.
Keywords: Breast milk; Extract
klabet (Trigonella foenum-graecum); Extract kelor (Moringa oleifera); Acute and
subchronic toxicity
Penulis: Lucie Widowati, M
Wien Winarno, Putri Retno Intan
Kode Jurnal: jpfarmasidd140568
