Health-Related Quality of Life of Type 2 Diabetes Mellitus Outpatients at Dr. Sardjito Hospital, Yogyakarta, Indonesia: An Insulin-Based Therapy Approach

Abstract: Diabetes mellitus type 2 is a lifelong disease which needs an intensive therapy to maintain stable blood sugar levels. Insulin has been proven as an effective treatment modality for type 2 diabetes mellitus patient. The main aim of this research was to evaluate the effect of insulin based therapy (insulin monotherapy-combination therapy of insulin with oral hypoglycemic agents) towards the health related quality of life in type 2 diabetes mellitus outpatient at Dr. Sardjito Hospital, Yogyakarta. This study is a descriptive cross-sectional study design without control. The methods of collecting data includes conducting questionnaires, interviews and examining medical records of patient. Data were taken concurrently from patients who visited Endocrinology Clinic of Dr. Sardjito Hospital from July 2012 until April 2013. Inclusion criteria for the participant were as follows: participant was a type 2 diabetes mellitus outpatient with insulin based therapy, had no languange barrier and was able to participate the study. Participants were excluded in this study if they had a mental and language retardation, uncomplete medical records, and was a pregnant woman. The quality of life was measured by Diabetes Quality of Life Clinical Trial Quessionnaire (DQLCTQ). The statistical analysis used in this study was Mann‑Whitney for QoL analysis based on the type of therapy (insulin monotherapy and combination therapy of insulin-oral hypoglycemic agents). The results from 137 patients shown that patients who received combination therapy had the largest percentage (73%) while the smallest percentage (27%) were single therapy. Whereas, the type of therapy (insulin monotherapy-combination therapy of insulin with oral hypoglycemic agent) significantly influenced the energy domain (p=0,027).
Keywords: Health related quality of life, insulin based therapy, type 2 diabetes mellitus
Penulis: Lolita, Tri M. Andayani
Kode Jurnal: jpfarmasidd170004

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