POTENSI FRAKSI ETIL ASETAT DAUN TORBANGUN (Coleus amboinicus L.) DALAM MENINGKATKAN PRODUKSI SUSU, BOBOT BADAN INDUK, DAN ANAK TIKUS
Abstract: The aims of the
research were to investigate the potential medicine from ethyl acetate fraction
of Coleus amboinicus L. for improving milk yield, body weight of rats and its
effects on growth of the rat pups. Galactagogue activity was evaluated in terms
of quantity of milk produced from the rats treated with ethyl acetate fraction
of torbangun leaves (FEA), and commercial milk booster contained ‘katuk’ leaves
extract (AF). Lactating rats (n=5) of Sprague dawley with six pups were fed
with FEA and AF in the amount of 30 mg/kg and 50 mg/kg body weight,
respectively. The feed were given orally every two days and starting from day 2
after giving birth until day 14. The performance of milk production was
measured along the experimental period by weight-suckle-weight method. The
rates of pups’ growth were measured as the weight gain along experimental
period. The rats fed with ethyl acetate fraction of torbangun leaves produced
higher milk than AF and the control groups, while FEA did not affected the body
weight of rats in comparison to the control groups. Ethyl acetate fraction of
torbangun leaves was identified to increase milk production by 17%, while AF by
22%. The mean of yields produced by the rats during lactation period for FEA,
AF and control were 7.12±1.16, 7.43±1.04 and 6.07±0.85 g/pups/day,
respectively. The FEA administration showed gradually increased of rat pups
growth and body weight gain significantly in pups 2-14 days old compared to the
control group. The present study reveals the ethyl acetate fraction has the
potency as a remedy for improving milk yield without influencing the rats.
Keywords: body weight; Coleus
amboinicus; fractionation; lactation; rat
Penulis: Ade Chandra Iwansyah,
Muhammad Rizal Martua Damanik, Lilik Kustiyah, Muhammad Hanafi
Kode Jurnal: jpkesmasdd170517
