Efficacy of Propolis Supplementation to Accelerate Healing Process and Body Weight Recovery of Pulmonary Tuberculosis Patients
Abstract: This study aimed to
evaluate the pace of curing process and body weight recovery of pulmonary
tuberculosis (Tb) patients receiving propolis supplementation. This study was a
randomized controlled trial conducted on 50 pulmonary Tb patients that were
assigned into three groups as follows: receiving standard-dose antituberculosis
drugs (ATDs) + 20 drops of placebo propolis (P0); receiving standard-dose ATDs
+ 20 drops of propolis with concentration of 6% (P1); and receiving
standard-dose ATDs + 20 drops of propolis with concentration of 30% (P2). The
results showed that the mean time ratio needed for sputum smear conversion to
negative present of acid resitant bacteria in P0, P1 and P2 groups were weeks
10, 8 and 5, respectively. In the second week, mean body weight of P0 and P1
groups decreased by 2.4% and 0.2%, respectively. In contrast, the mean body
weight in P2 group increased by 1.5% (p<0.05; Mann-Whitney test). In the
same week, mean body mass index (BMI) of P0 and P1 groups decreased by 1.6 and
0.1, respectively. Conversely, the mean BMI of P2 group increased by 0.3. The
changes were significantly different (p<0.05). The results conclusively indicated
that supplementation of 20 drops of propolis with a concentration of 30% as an
adjuvant to standard ATDs for the treatment of pulmonary Tb patients was
beneficial to accelerate treatment effect and body weight recovery.
Keywords: body
weight; healing; liquid propolis; pulmonary Tb
Mahani, Ahmad Sulaeman, Faisal
Anwar, Muhamad Rizal Martua Damanik, Hardinsyah, Angelika Ploeger
Journal Code: jpkesmasgg180019
