Perbedaan arus puncak ekspirasi antara anak asma dengan obesitas dan anak asma tanpa obesitas
Abstract: Obesity in children
is associated with impairment of pulmonary function and increased risk of
asthma. Obesity in asthmatic children may reduce lung function, that can be
assessed by peak flow meter, a practical and an inexpensive tool.
Objectives: To compare the peak expiratory flow (PEF) between obese and
non-obese asthmatic children.
Method: We conducted a cross sectional study in Yogyakarta during March
2010-September 2012. Fifty obese asthmatic patients and 50 non obese asthmatic
control subjects participated in this study. Inclusion criteria were asthmatic
patient, according to Pedoman Nasional Asma Anak (PNAA), and 6-18 years of age.
Exclusion criteria were asthmatic attack, respiratory disease, heart disease
and congenital chest malformation. Obesity is defined as body mass index (BMI)
for age more than +3 SD WHO growth chart standards BMI for age 2007 z-score. Z-score
is calculated with WHO AnthroPlus for Personal Computers. Data PEF is taken
with electrical peak flow meter when the patient was not suffering from asthma
attack. Normal PEF was defined as PEF ≥80% average (predicted) value for
height.
Results: The mean of age of asthmatic children in this study was 9.38
years and 9.50 years for non obese and obese respectively. The PFR was not
different between obese asthmatic children and non obese asthmatic children
(p=0,83). Pearson correlation of PFR and z-score BMI for age was positive weak
correlation (r=0.12). There was significant difference of PFR between z-score
BMI for age <3,20 and z-score BMI for age ≥3.20 (p=0.03). Significant
difference of PFR also appears in duration of illness (p<0.001).
Conclusion: There is no PFR difference between obese asthmatic children
and non-obese asthmatic children. The difference of PFR emerges when statistic
analysis performed using z-score BMI ≥3.20.
Keywords: peak flow rate;
obesity; asthma; children
Penulis: Nurul Hadi
Kode Jurnal: jpkesmasdd130683
