Asupan makan, sindrom metabolik, dan status keseimbangan asam-basa pada lansia
Abstract: Metabolic syndrome
prevalence increases with age and obesity. The metabolic syndrome is associated
with alterations in renal function. Low urine pH has been described as a renal
manifestation of the metabolic syndrome. Urine pH is a simple and inexpensive method
for determining acid-base status. Recent studies suggest that acid-base status
is associated with dietary intake.
Objective: To examine relationship between dietary intake, components of
metabolic syndrome and urine pH among the elderly.
Method: Subjects of this cross-sectional study consist of 49 elderly that
were collected consecutively. Height, weight, waist circumference (WC), dietary
intake, blood pressure (BP), fasting blood glucose and urine were obtained.
Rank Spearman correlation test was used to examine the correlation of
components of metabolic syndrome and dietary intake with urine pH. Mann-Whitney
test was used to compare the urine pH of the metabolic syndrome group and the
normal group. Chi-Square/fisher test was used to calculate prevalence ratio
(PR) of metabolic syndrome components to low urine pH. Multivariate analysis
was done by multiple linear regression.
Results: The mean urine pH of the metabolic syndrome group was 6,06 and
significantly lower than the normal group (6,50). WC was the only component of
metabolic syndrome that related to urine pH (r=-0,325; p=0,023). Abdominal
obesity significantly increases the risk of low urine pH (RP=1,6; p=0,023;
CI=1,005-2,442). Urine pH was negatively associated with protein intake and
proportion of protein on diet. In multivariate analysis, WC is the most
significant factor that predicted urinary pH.
Conclusion: Urine acidification is a characteristic of abdominal obesity
and the metabolic syndrome. Protein intake and proportion of protein on diet
contribute to urine pH.
Keywords: metabolic syndrome;
abdominal obesity; low urine pH; protein intake
Penulis: Nurmasari Widyastuti
Kode Jurnal: jpkesmasdd130678
