Comparison of Coronary Angiography Characteristics among Acute Coronary Syndrome Patients in Young and Old Age Patients at Cipto Mangunkusumo Hospital Jakarta
Abstract: to identify the
difference between coronary angiography in patients with acute coronary
syndrome (ACS) aged ≤45 years and those aged >45 years. Methods: a total of
322 ACS patients who underwent coronary angiography in ICCU of Cipto
Mangunkusumo Hospital, Jakarta between January 2008 and December 2012 were
included in this study. The severity of coronary stenosis was determined by
vessel score and coronary score. A significant vessel score was defined as a
stenosis of coronary vessel of >70%. Patients were divided into two groups:
those aged ≤45 years (72 cases) and those aged >45 years (250 cases). The
statistical analysis was performed with Chi-square test for categorical data
with two-unpaired groups and the t-test or Mann-Whitney for numerical data.
Results: the highest distribution of 1-VD (single-vessel disease) patients was
found the group of patients aged ≤45 years (43.1% vs 26.0%); while for 3-VD
(triple-vessel disease) patients, the highest distribution was noticed in the
group of patients aged >45 years (31.6% vs 18.1%). The stenosis score was
lower in patients aged ≤45 years compared those aged >45 years (median
stenosis score 4 vs 8), p<0.001. Atherosclerosis was found most common for
the left anterior descending artery in both age groups (65.3% and 74.0%).
However, there was less significant stenosis lesion for the Left Circumflex and
Right Coronary Arteries in patients aged ≤45. The result was statistically
significant (26.4% and 31.9% vs 46.4% and 57.2%, p=0.002 and 0.001).
Conclusion: the number of coronary artery diseases (vessel score) and stenosis
score is lower in patients aged ≤45 years compared to patients aged >45
years.
Key words: acute coronary
syndrome, coronary angiography, young age
Author: Rahmad Isnanta,
Marulam M Panggabean, Idrus Alwi
Journal Code: jpkedokterangg140311
