Cellular Cardiomyoplasty For Myocardial Infarction: a 2014 Evidence-based Update
Abstract: Myocardial
infarction is one of the main cause of mortality in many countries. Therefore,
an effective therapy for myocardial infarction is required. Reperfusion and
other conventional therapy have been the mainstay therapy for myocardial
infarction. However, many patients remain refractory to this therapy. Cellular
cardiomyoplasty is considered a novel therapy, in which stem cells are used for
cardiac repair. Stem cells are potential therapeutic approach that could be the
ultimate solution for salvaging damaged cardiomyocyte.
Based on current studies, stem cells are a promising therapeutic approach
for myocardial infarction. However, some challenges need to be answered by
future studies before this novel therapy can be widely applied. As we advance
our understanding, all questions behind stem cell therapy would finally be
revealed, and eventually provide the ultimate solution for ischaemic cardiac
repair. This paper provide an overview of the latest progress in stem cell
therapy for myocardial infarction.
Key words: stem cells,
cellular cardiomyoplasty, myocardial infarction
Author: Alvin Nursalim,
Puspita A Katili, Teguh Santoso
Journal Code: jpkedokterangg140317
