Two Years Profile of Anemia in Systemic Lupus Erythematosus Patients at West Java’s Top Referral Hospital, Indonesia
Abstract: Anemia is a common
clinical manifestation in Systemic Lupus Erythematosus (SLE) patients. Anemia
can be caused by an ineffective hematopoietic process or excessive red blood
cell destruction. The aim of this study was to classify and characterize anemia
in SLE patients.
Methods: This study involved 97 outpatients visiting the Rheumatology
Clinic of Dr. Hasan Sadikin General Hospital Bandung, from January 2013 to
September 2014. Patient data was collected from medical records and study
subjects were selected according to the American College of Rheumatology 1997
criteria for SLE, and the characteristic of anemia among outpatients were
described according to the World Health Organization criteria.
Results: The characteristics among 97 respondents showed 95 (98%) were
female; 32 (33%) were 21–30 years old; and 49 (51%) had SLE for 1–5 years. The
characteristics and classification of anemia, 57 (59%) had normocytic
normochromic, and 33 (34%) had microcytic hypochromic anemia. According to the
severity classification, 48 (50 %) had moderate anemia, only 8 (8%) had severe
anemia. Four (4%) subjects had anemic conjunctiva, 45 (46%) had fatigue and 48
(50%) had no clinical manifestations of anemic conjunctiva and fatigue.
Conclusions: Moderate anemia, normocytic normochromic anemia are the most
prevalent among the subjects. Half of the anemic SLE patient has no clinical
manifestation of anemic conjunctiva and fatigue.
Keywords: Anemia, anemic
conjuctivasystemic lupus erythematosus, fatigue
Author: Stefanie Yuliana
Usman, Laniyati Hamijoyo, Anna Tjandrawati
Journal Code: jpkedokterangg170135