Treatment Failure of Ampicillin to Children with Pneumonia at Dr. Hasan Sadikin General Hospital Bandung from 2014–2015
Abstract: Pneumonia is one of
the causes of death in infants in developing countries especially Indonesia.
Appropriate treatment is needed to decrease mortality rate in children due to
pneumonia. Ampicillin is one of first choices empirical antibiotic to children
with severe pneumonia. The study was aimed to determine the failure rate of
ampicillin in children with severe pneumonia.
Methods: This study was a descriptive study which used medical records as
source of data. Subjects were children aged 2–59 months with World Health
Organization (WHO) defined with severe pneumonia and treated with intravenous
ampicillin during January 2014 to July 2015 at Dr. Hasan Sadikin General
Hospital Bandung. Samples were obtained using total sampling method while
variables were analyzed using statistics software.
Results: This study acquired 107 patients who met the inclusion criteria
with 23.36% of them aged 2–11 months and 62.21% aged 12–23 months. Majority of
subjects were male amounted as 63.55% while female occupied 36.45%. Treatment
failure on the third day was 45.8% while 16.7% on the sixth day of therapy with
majority failure due to existence of lower chest indrawing.
Conclusions: Treatment failure on the third and sixth day of therapy
still high that is characterized by the existence of lower chest indrawing as
its main factor.
Keywords: Ampicillin,
pneumonia, treatment failure
Author: Kania Devi Suharno,
Ike Rostikawati Husen, Sri Sudarwati
Journal Code: jpkedokterangg170094
