The Prevalence of Antibiotic and Toothpaste Sensitivity found in Oral Streptococcal Isolates in Healthy Individuals in the Okada Community of Nigeria
Abstract: This study aimed to
determine the prevalence, antibiotic, and toothpaste sensitivity of oral
streptococcal isolates in healthy individuals in the Okada community of
Nigeria. Methods: Oral samples were collected from 230 volunteers and were
subjected to standard microbiological tests. Antibacterial sensitivity tests
were carried out on the streptococcal isolates that were obtained using a disk
diffusion technique, and eight kinds of toothpaste (A-H) were screened for
their antibacterial effects on Streptococcus mutans (S. mutans). Results: The
prevalence of oral streptococci found in this study was 26.1% and the
predominant species was S. salivarius (13.9%). S. salivarius was highly
resistant to cloxacillin (100%) and Augmentin (96.9%), whilst resistance to
gentamicin and erythromycin was low at 21.9% and 3.1% respectively. S. mutans
were completely sensitive to gentamicin whilst resistance to erythromycin was
33.3%. The entire Streptococcus species showed the lowest resistance to
erythromycin (20.0%), followed by gentamicin (31.7%). At 100 mg/mL all
toothpaste samples had antibacterial effects on S. mutans. At 50 mg/mL all
samples except toothpastes G and H inhibited the bacterium. Toothpastes A and E
had the lowest minimum inhibitory concentration of 25 mg/mL. Conclusions:
Toothpastes A and E were the most effective toothpastes of the eight assessed
in this study.
Keywords: antibiotics; dental
caries; fluorides, oral streptococci; thymol; toothpastes
Author: Maureen U Okwu, Olley
Mitsan
Journal Code: jpkedokterangg170241
