THE EFFECT OF PERIOPERATIVE AND PROPHYLACTIC ANTIBIOTICS AGAINST THE INCIDENCE OF UTI AND SURGICAL SITE INFECTIONS AFTER HYPOSPADIAS SURGERY
Abstract: The aim of this study
is to analyze the effect of perioperative and prophylactic antibiotics against
the incidence of urinary tract infections (UTI) and surgical site infections
(SSI) after hypospadias surgery (hypospadias repair operation). Materials &
Methods: This study is an observational study of explanation with 24
hypospadias patients (2 groups) during the period of October 2015 to February
2016. Samples were divided into two groups, 12 patients received prophylactic
antibiotics and 12 patients received perioperative antibiotics (random
sampling). Inclusion criteria included patients with glandular hypospadias to
proximal penile hypospadias, aged 6 months until 15 years and underwent
hypospadias surgery with one surgical technique namely Tubularized Incised
Plate (TIP). The examination of urine culture and evaluation of the wounds were
performed on day 4, 10, and 20 day after surgery to determine the incidence of
urinary tract infections and surgical site infections. Results: There is no
significant difference in the incidence of UTI on on day 4, 10 and 20 in perioperative group and prophylaxis group
with p=0.282 and p=0.500 at day 4 and 10
(p>0.05). There is no significant difference in the incidence of SSI
on day 4, 10 and 20 in the group of perioperative antibiotic and prophylactic
antibiotic with p=0.680 and p=0.217 at day 4 and 10 (p>0.05). Conclusion:
There is no effect of the prophylactic antibiotic as well as perioperative
antibiotic treatment on the incidence of UTI and SSI
Keywords: Urinary tract
infection; surgical site infection; hypospadias; tubularized incised plate
Author: Raditya Kusuma, Johan
Renaldo, Tarmono Djojodimedjo, Sunaryo Hardjowijoto
Journal Code: jpkedokterangg170015