The Administration of Garlic Extract on Eimeria stiedai Oocysts and the Hematological Profile of the Coccidia Infected Rabbits
Abstract: This research aimed
to examine the potential of garlic as the coccidiosis control in rabbits either
in vitro or in vivo. During in vitro, observed variables were rabbits oocysts
that were sporulated, unsporulated, and abnormal in incubation for 3 days with
the addition of garlic extract. The treatments were doses of garlic extract
administration (0%, 1%, 2%, 4%, and 8%) and sulfaquinoxalline as a standard
anticoccidiosis. Meanwhile during in vivo, the variables observed were the
hematological profile of the experimental rabbits naturally infected with
coccidia. The doses of garlic extract was administered orally to the
experimental rabbits infected with coccidia were 0 mg, 10 mg, 20 mg, 40 mg, and
80 mg/rabbit. As a standard coccidiosis
drugs, the combination of sulfadiazine and trimethoprim was used. The treatments were given for 6 days. The
variables observed were the hematological profile of the coccidiosis rabbits,
including the erythrocytes, hemoglobin, hematocrits, MCV, MCH, MCHC, and
thrombocytes. The research employed a completely randomized design, with 5
repetitions. The data were further analyzed using the honestly significant
difference test. The results showed that garlic extract administration
significantly decreased (P<0.01) both the number of the sporulated and
unsporulated oocysts (P<0.05), yet did not significantly influence the
abnormal oocysts, but there was no significant difference within the entire
hematological variables except in thrombocytes (P<0.05). Garlic extract
administration decreased the excretion number of oocysts in the feces either in
vitro or in vivo and influenced some hematological variables which provided a
new propect for controlling coccidiosis naturally in rabbits.
Keywords: coccidia; rabbits;
garlic extract; oocyst; hematology
Author: D. Indrasanti, M.
Indradji, S. Hastuti, E. Aprilliyani, Fatikha Fatikha, K. A. Rosyadi
Journal Code: jppeternakangg170068