Phytochemical Screening and in Vitro Ovicidal, Larvacidal, and Nematicidal Effects of Murraya paniculata (L.) Jack Extract on Gastrointestinal Parasites of Goats
Abstract: In our previous
research, kemuning leaves (Murraya paniculata L. Jack) was shown to have the
capability as an anthelmintic candidate for PE (Ettawa crossbred) lactating
dairy goats by reducing 43.67% of the egg per gram (EPG) of Strongylida
compared to 0.0005% in orally treated with Oxfendazole as a control. To confirm
it, the aim of this in vitro study was to determine the effective dosage of
kemuning leaves from two extraction methods (infuse and maceration) to reduce
the Trichostrongylidae and to evaluate the bioactive compounds of the leaves.
The research was conducted using a randomized complete design with 11 treatments
and 5 replications. The treatments consisted of control (0.0005% and 0.005%
Oxfendazole), kemuning leaves infuse extract (KIE) and maceration extract (KME)
each with level of 1%, 3%, 5%, and 7% (w/v). The results showed that the LT50
gradually decreased (shortening the lethal time) and the mortality of
Trichostrongylidae gradually increased associated with the increased
concentration of treatment (P<0.01). The infusion of 7% kemuning extract
demonstrated the highest efficiency in reducing the larval development,
infective larvae, and the adult Trichostrongylidae by 93.16%, 94.39%, and 90%,
respectively. This treatment could be
developed as the most prospective herbal anthelmintic drug in controlling the
infection by Trichostrongylidae.
Keywords: infusion; kemuning
(Murraya paniculata L. Jack); maceration; Trichostrongylidae
Penulis: G. E. Tresia, D.
Evvyernie, R. Tiuria
Kode Jurnal: jppeternakangg160052
