Performance of osteoporosis self-assessment tool in detecting low bone mineral density in menopausal women
Abstract: The osteoporosis
self-assessment tool (OST) is a simple screening tool to assess risk of
osteoporosis and to select high risk women for dual-energy x-ray absorptiometry
(DXA) examination. This study aimed to evaluate OST performance in detecting
low bone mineral density (BMD) in menopausal women.
Methods
A cross-sectional study involving 60 menopausal women aged 50-65 years.
The OST score was calculated from: [weight (kg) – age (yr)] x 0.2. Subjects
were classified by OST score into low risk (OST ³2) and high risk (OST< 2)
groups. BMD was determined by DXA at 3 bone locations (L1-L4, femoral neck, and
total hip). DXA T-scores were categorized into: normal BMD (T-score >-1) and
low BMD (T-score £-1). Independent t-test was used to compare subject
characteristics between OST groups. Diagnostic performance of OST was evaluated
by measuring sensitivity, specificity, positive & negative predictive value
(PPV, NPV), positive & negative likelihood ratio (PLR, NLR) and
receiver-operating characteristic (ROC). Significance was set at p<0.05.
Results
Subject characteristics and BMD between groups were significantly
different (p<0.05). Most subjects (44/73.3%) had high risk of low BMD (OST
< 2). Low BMD (T score £-1) was found in 43 subjects (71.7%) at L1-L4, 41
subjects (68.3%) at femoral neck, and 37 subjects (61.7%) at total hip.
Diagnostic performance of OST was significant at total hip BMD
(sensitivity=0.946, AUC=0.777).
Conclusion
We conclude that use of the OST score in menopausal women is effective
and has adequate sensitivity and specificity. The highest diagnostic
performance of OST is on total hip BMD.
Keywords: Bone mass;
menopausal women; simple screening tools
Author: Ignatio Rika Haryono,
Nawanto Agung Prastowo
Journal Code: jpkedokterangg170041
