Penatalaksanaan Pasien Erupsi Obat di Instalasi Rawat Inap (IRNA) Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya: Studi Retrospektif
ABSTRACT: Drug eruption is a skin alteration with or
without the involvement of other organ, which appeared after administration of
drug at dose used for prevention, diagnosis, or treatment. The mechanism
divided into 2 groups, which are type A (can be predicted) and type B (can not
be predicted). Purpose: To evaluate the
management of drug eruption in Dermatovenereology Ward at Dr. Soetomo General
Hospital Surabaya. Methods: Retrospective study of drug eruption's patients was
performed based on medical records within 2009-2011. Basic data, history of
allergies, previous medical history, suspected drugs, diagnosis, and previous
treatment were recorded. Results: The largest age group is 25-44 years, ratio
of women and men is 1.4: 1, most suspected drugs as the cause of the eruption
were paracetamol (59), amoxicillin (23), cefadroxil (17). Most common diagnosis
was Steven-Johnson syndrome (SJS) as many as 23.4%, the most widely used
treatment was steroids, and the average treatment duration was 10 days. Drug
patch test (DPT) was conducted to determine the exact cause of drug eruption as
the follow up. Conclusion: Drug eruptions can occur in varying degrees,
potential to recur, and life-threatening thus appropriate treatment to prevent
it is required. Management included given treatment, patient education
regarding drug eruption causes, type of eruption, and DPT to determine the
cause of drug eruption.
Key words: drug eruptions,
management, drug patch test (DPT), retrospective study
Kode Jurnal: jpkedokterandd150702
