Management of overactive bladder review: the role of percutaneous tibial nerve stimulation
Abstract: Overactive bladder
(OAB) is a common condition that is experienced by around 455 million people
(11% of the world population) and associated with significant impact in
patients’ quality of life. The first line treatments of OAB are conservative
treatment and anti-muscarinic medication. For the refractory OAB patients, the
treatment options available are surgical therapy, electrical stimulation, and
botulinum toxin injection. Among them, percutaneous tibial nerve stimulation
(PTNS) is a minimally invasive option that aims to stimulate sacral nerve
plexus, a group of nerve that is responsible for regulation of bladder
function. After its approval by food and drug administration (FDA) in 2007,
PTNS revealed considerable promise in OAB management. In this review, several
non-comparative and comparative studies comparing PTNS with sham procedure,
anti-muscarinic therapy, and multimodal therapy combining PTNS and
anti-muscarinic had supportive data to this consideration.
Keywords: electrical
stimulation overactive bladder; percutaneous tibial nerve stimulation
Author: Elita Wibisono,
Harrina E. Rahardjo
Journal Code: jpkedokterangg160309
