Lipid Profile in Type 2-Diabetic Women with Central Obesity and Non-central Obesity
Abstract: Type 2 Diabetes
Mellitus and central obesity are associated with higher risk of cardiovascular
diseases especially in women. Lipid profile may reflect dyslipidemia which
includes hypertriglyceridemia, increased level of LDL-C, total cholesterol, and
reduced HDL-C level in the blood. Patients with central obesity tend to have
dyslipidemia compared to those without central obesity counterpart. The study
aimed at comparing lipid profile in central-obese diabetic women and
non–central-obese diabetic women.
Methods: This study was an analytical study with cross–sectional approach
conducted in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia in 2013. A
total of 160 data contained of waist circumference (WC) and the level of total
cholesterol, triglyceride, HDL-C and LDL-C were obtained from medical record of
Diabetic patients within the period of January 2010–January 2012. Women
patients whose WC of ≥80 cm were classified as central obesity while WC of
<80 cm were classified as non-central obesity. The t-test was used to
compare means of different variables, p<0.05 was considered as statistically
significant.
Results: Central obese diabetic women when compared to non-central obese
diabetic women showed statistically significant increase in the level of total
cholesterol serum, triglyceride serum and decrease in HDL-C serum level
(p<0.05). The LDL-C serum level did not show statistical significant
difference in the two groups (p>0.05).
Conclusions: Diabetic patients with central obesity tend to have higher
level of total cholesterol and triglyceride and lower level of HDL-C compared
to diabetic patients without central obesity.
Keywords: Central obesity,
diabetic women, lipid profile
Author: Scholastica Diana
Nurvitasari, Nanny Natalia MS, Yovi Yoanita
Journal Code: jpkedokterangg160289
