High skeletal muscle mass is associated with increased serum 25(OH)D levels in elderly
Abstract: Low vitamin D has
been associated with various health problems. Aging influences body
composition, especially body fat and fat-free mass. Anthropometric
measurements, such as body weight (BW), body mass index (BMI), body fat (BF),
skeletal muscle mass (SMM), waist circumference (WC) and the waist-height ratio
(WHtR) represent body composition which many studies proposed will influence
serum vitamin D [25(OH)D]. The objective of the present study was to determine
which anthropometric measurements were determinants of 25(OH)D levels in
elderly.
Methods
A cross-sectional study was conducted involving 126 elderly (>60 years
old) men and women at Pusat Santunan Dalam Keluarga (PUSAKA) Central Jakarta
centers. Anthropometric measurements [body mass index (BMI), skeletal muscle
mass (SMM), body fat (BF), and waist circumference (WC)] were determined by
bioelectrical impedance analysis using the Omron body composition monitor with
scales (HBF-375, Omron, Japan). Fasting blood samples were taken to measure
25(OH)D level by electrochemiluminescence immunoassay. Multivariate linear
regression was used to analyze the data.
Results
The data showed that BMI, BF, and WC were higher than recommended, while
SMM and serum 25(OH)D were lower. When the analysis was done based on sex,
there were significant differences in BF, SMM, WHtR, and serum 25(OH)D. In the
linear regression multivariate analysis of log 25(OH)D with age and body
anthropometric measurements, only SMM reached significance level (β=0.019;
p=0.025).
Conclusions
This study demonstrated a positive association between skeletal muscle
mass and serum levels of vitamin D in elderly.
Keywords: 25(OH)D; elderly;
sex; anthropometric measurements
Author: Verawati Sudarma,
Lukman Halim
Journal Code: jpkedokterangg170058
