Gambaran Histologis Hepar Mencit Jantan (Mus musculus) yang diberi Ekstrak Ethanol Propolis
Abstract: The aim of this
research was to fnd out the effects of propolis on histological liverin male
mice (mus musculus). This research used 25 male mice which are 12 weeks oldwhich
has 25-35 g of body weight. They were divided randomly into fve groups. (P0) asa
control was given tween 80 0.5 ml/KgBW/day, and other group were given propolis
for(P1) 0,4 mg /KgBW/day, (P2) 0,8 mg /KgBW/day, (P3) 1,6 mg / KgBW/day, and
(P4) 3,2 mg / KgBW/day. After two weeks treatment, the mice eutiniced by
cervical dislocation and then took the liver for the histological preparations.
The histological staining used H.E.The data were analyzed by Kruskall-Wallis
method based on Completely RandomizedDesign, and further analyzed by Z test.
The result from statistical analysis showed that treatment with propolis effect
on histological liver in male mice did not give a bad effecton the body, so the
propolis is safe for consumption.
Keywords: Propolis, liver, mice,
histological
Penulis: Bagus Pandu Satrio
Utomo
Kode Jurnal: jppeternakandd170055