Diagnostic Value of Narrow Band Imaging in Diagnosing Nasopharyngeal Carcinoma
Abstract: Carcinoma is the
most common tumor in nasopharynx. Endoscopy is used to determine the presence
of lesions suspected of malignancy. Narrow Band Imaging is an endoscopic
technique that uses narrow–band spectrum as a filter to determine any mucosal
vascular changes in carcinoma. Narrow Band Imaging can early detect superficial
mucosal lesions that are difficult to detect with conventional endoscopy, so
that diagnosing is more accurate and occurrence of unnecessary biopsies can be
reduced. This study aimed to determine diagnostic value of Narrow Band Imaging
in diagnosing nasopharyngeal carcinoma.
Methods: This diagnostic test study was conducted at Department of
Otorhinolaryngology-Head and Neck Surgery Dr. Hasan Sadikin General Hospital,
Bandung from September to October 2014. Twenty four patients with clinical
signs and symptoms of nasopharyngeal carcinoma that fulfilled the study
criteria were assigned using consecutive sampling to examine with Narrow Band
Imaging and histopathology examination. The data were then analyzed with 2x2
table to determine sensitivity, specificity, positive predictive value,
negative predictive value, and accuracy.
Results: In this study, the results of sensitivity, specificity, positive
predictive value, negative predictive value, and accuracy in diagnosing
nasopharyngeal carcinoma using Narrow Band Imaging were 93.75%, 62.5%, 83.3%,
83.3%, and 83.3%, respectively.
Conclusions: Sensitivity of Narrow Band Imaging is 93.75%.
Keywords: Diagnostic test,
narrow band imaging, nasopharyngeal carcinoma
Author: Debbi Yuniserani,
Bethy S. Hernowo, Agung Dinasti Permana
Journal Code: jpkedokterangg170100
