Detection of Insecticide Resistance in Aedes Aegypti to Organophosphate in Pulogadung, East Jakarta
Abstract: Dengue Hemorrhagic
Fever (DHF) is a major public health problem in Indonesia. Jakarta is a capital
city with the highest number of dengue patients. Among sporadic endemic areas
in Jakarta, Pulogadung, a district of East Jakarta, is one of endemic areas of
this disease. The primary strategy for the control of DHF is based on reducing
population densities of the main mosquito vector Aedes aegypti. Organophosphate
is an insecticide that has been used for more than 25 years in dengue vector
control program. The long term used and sublethal dosage of this insecticide
can induce resistance. This laboratory study used microplate test and ELISA
reader to determine the increase of alfa- esterase activity in Aedes aegypti
larvae for detecting the resistance to organophosphate. Resistance pattern of
Ae aegypti to organophosphate insecticide in RW 01 Pulogadung was shown to be:
23% high resistant, 33% medium resistant and 44% sensitive. This result was
highly related to local community behavior where we found that the use of
insecticide spray by the people was very low (8.8% of the sample). We found
that the people who used insecticide spray were only 8.8% of the sample.
Therefore, organophosphate still can be used in this area to control the Dengue
Hemorrhagic Fever in the future. Based on resistance pattern of Ae aegypti to
organophosphate insecticide in RW 01 Pulogadung, we can conclude that
organophosphate still can be used in this area to control the Dengue Hemorrhagic
Fever in the future.
Keywords: Aedes aegypti;
insecticide; larvae; resistance; organophosphate
Author: Ambar Hardjanti, Isna
Indrawati, Elita Donanti, Heri Wibowo, Zulhasril
Journal Code: jpkedokterangg150383