COMPARISON OF EFFECTIVENESS OF MELOXICAM 15 MG ONLY, COMBINATION OF MELOXICAM 15 MG AND TAMSULOSIN 0.4 MG, AND TAMSULOSIN 0.4 MG ONLY FOR SUCCESS OF TWOC IN BPH PATIENTS WITH FIRST EPISODE OF ACUTE URINARY RETENTION
Abstract: To prove that
Meloxicam 15 mg only, combination of Meloxicam 15 mg and Tamsulosin 0.4 mg were
more effective for the success of Trial Without Catheter (TWOC) in BPH patients
with first episode of urinary retention compared to Tamsulosin 0.4 mg only.
Material & methods: Benign Prostatic Hyperplasia (BPH) patients with first
episode of urinary retention that met the inclusion criteria and did not fulfill
the exclusion criteria were randomized to form 3 treatment groups, n=11 for
each group. Group I was given Meloxicam 15 mg only, group II was given a
combination of Meloxicam 15 mg and Tamsulosin 0.4 mg, and group III was given
Tamsulosin 0.4 mg only. For each group the drug given once orally for 7 days.
The success of TWOC assessed by an ability to spontaneous micturition after
that each treatment in the first 24 hours after urethral catheter removal,
accompanied by Qmax in uroflowmetry ≥ 5 cc/sec and PVR ≤ 100 cc. Results: All
Meloxicam 15 mg only group samples have recurred urinary retention (100%). The
success rate of TWOC for combination of Meloxicam 15 mg and Tamsulosin 0.4 mg
group was 72.7%; while for the Tamsulosin 0.4 mg only one was 63.6%. The success
rate of TWOC for combination of Meloxicam 15 mg and Tamsulosin 0.4 mg group was
higher than Tamsulosin 0.4 mg only one (p=0.003). Conclusion: The combination
of Meloxicam 15 mg and Tamsulosin 0.4 mg orally once daily for 7 days was more
effective in the success of TWOC in BPH patients with first episode of urinary
retention compared to Tamsulosin 0.4 mg only orally once daily for 7 days.
Keywords: Trial without
catheter; Meloxicam; Tamsulosin; combination; Benign Prostatic Hyperplasia;
urinary retention; first episode
Author: Muhammad Asro Abdih
Yasa, Doddy M Soebadi, Fikri Rizaldi
Journal Code: jpkedokterangg180012
