Association between Patient’s Basic Characteristic and Clark Level in Cutaneous Malignant Melanoma
Abstract: Malignant melanoma
is a cancer that begins in the
melanocytes. Melanoma is commonly happened on older people, male and located on
sun exposure body area, such as face, neck and lower limb. Melanoma cases occur
less than 5% of skin cancer but cause a majority of skin cancer deaths because
melanoma has an aggressive behavior. Age, sex, location of lesion, and type of
melanoma influences the melanoma invasion. The cutaneous melanoma invasion
could be assessed with the Clark level. This study is aimed to determine the
association between patient’s basic characteristic and Clark level in cutaneous
malignant melanoma.
Methods: This study used cross sectional analytic design. The medical
records and histopathology slide from the Department of Anatomic Pathology Dr.
Hasan Sadikin General Hospital from 2008−2012 took as a sample. Forty one data
were meet the inclusion criteria.
Furthermore, those data were analyzed using chi-square test.
Result: Overall, patient’s characteristic in this study, commonly
occurred on female (66%), 50−59 years group age (35%), non-cephalic/acral
location (71%), and the level V in Clark level (73%). Location of lesion showed
an association with Clark level (p=0.023), whereas, age and sex was not
significant (p=0.679 and p=0.389).
Conclusions: There is an association between location of lesion and Clark
level
Keywords: Basic
characteristic, cutaneous melanoma, Clark level, malignant melanoma
Author: Egie Rahmalaelani,
Hermin Aminah Usman, Jono Hadi Agusni
Journal Code: jpkedokterangg170078