Antimicrobial Sensitivity of Neonatal Bacterial Sepsis
Abstract: Appropriate
treatment on neonatal bacterial sepsis is important based on the exact etiology
to prevent bacterial resistance, but bacterial identification using blood
cultures requires a considerable time. The newest data of various bacteria and
their sensitivity can be used to assist empirical antibiotics usage. This study
was conducted to identify bacterial profile that caused neonatal sepsis and
their sensitivity to antibiotics at Dr. Hasan Sadikin General Hospital
Bandung..
Methods: A total of 275 neonatal sepsis cases and 288 blood cultures
results were collected from a database provided by Dr. Hasan Sadikin General
Hospital Bandung during the period of July 2011 toDecember 2012 (three
semesters). Etiology of the bacteria and
antimicrobial sensitivity profile data were taken from positive bacteria
results. Then, these variables were processed using the descriptive method and
classified by semester
Result: The most common bacteria that caused neonatal sepsis in the
second semester 2011 is Serratia marescens, the first semester 2012 was
Enterobacter aerogenes and in the second semester 2012 was Burkholderia
cepacia. The most sensitive antibiotics were piperacillin tazobactam, cefepime,
meropenem and amikacin in all three semesters, gentamycin in the second
semester 2011 and 2012, and amoxicillin clavulanic in the second semester 2012.
Conclusions: Bacterial and antimicrobial sensitivity profile is varied in
every semester.
Keywords: Antimicrobial
sensitivity profile, bacterial profile, neonatal sepsis
Author: Nadya Iswandari, Aris
Primadi, Sunarjati Sudigdoadi
Journal Code: jpkedokterangg170111
