A Cross-Sectional Study of the Candidal Species Isolated in the Oral Cavities of Type II Diabetic Patients
Abstract: The objectives of
this study were to determine the prevalence and colonisation of Candida species
and to study the factors related to candidal colonisation in the oral cavity
among type II diabetic patients. Methods: The data of 102 diabetic patients was
collected from the Outpatient Diabetic Clinic at the Naresuan University
Hospital. Data was collected via a questionnaire and oral examination. The
subjects were measured for their fasting blood sugar levels and salivary pH.
Candida colonisation was assessed using saliva sampling, and was cultured on
CHROMagar Candida plates. Species and colony forming unit/mL were recorded.
Results: The results showed that the prevalence of oral Candida species in
diabetic patients was 73.5%. The most frequent candidal species in diabetics
were Candida albicans (68.6%), followed by C. glabrata (28.4%), C. tropicalis
(10.8%), and C. krusei (2.0%) respectively. There was no statistical
significance between the fasting plasma glucose levels and oral Candida species
colonisation. Logistic regression showed that a decrease of the salivary pH was
related to the colonisation of candidal species. Results showed that the use of
a dental prosthesis was a related factor to the colonisation of candidal
species (p < 0.05). Conclusions: A high prevalence of candidal species were
found in type II diabetic patients. Salivary pH and use of a dental prosthesis
are factors that promote candidal infections in type II diabetic patients
Keywords: Candida, denture,
diabetes mellitus oral health, oral thrush
Author: Patcharaphol Samnieng,
Sita Sonthayasathapon, Masjutha Siriwat, Supanee Jeamanukulkit
Journal Code: jpkedokterangg170257
