A Clinical Profile of Hepatitis A Patients in Jakarta, Indonesia
Abstract: To determine the
incidence of hepatitis A infections and the clinical profiles of adult patients
admitted to public hospitals in Jakarta, Indonesia. Methods: This was a
cross-sectional study that utilised consecutive secondary data from internal medicine
wards of seven public hospitals in Jakarta between 2011 and 2013. Eligibility
criteria included patients over the age of 18 years and an ICD-10 diagnosis
code of B15, acute hepatitis A. Case proportion was reported per 1000 people by
dividing incidence per year to total in-ward patients. Clinical profiles were
reported descriptively. Laboratory results were compared and categorised into
groups of patients aged below and above 25 years old. Results: Data revealed
that hospitalisations of patients with hepatitis A had decreased from 2011 to
2013. 289 patients were studied, the majority were young adults (18-25 years
old) and their common chief complaints were nausea (36%), fever (24%), and
jaundice (21%). Higher bilirubin levels were seen in older patients. There were
13 patients coinfected with hepatitis B, one patient coinfected with hepatitis
C, and one patient coinfected with HIV. Conclusions: The proportion of
hepatitis A infection amongst adults admitted to public hospitals in Jakarta
was low and had decreased during the study period. Most of the patients
reported classical clinical manifestations. This study found that the targeted
age group may benefit from receiving routine hepatitis A vaccinations.
Keywords: epidemiology;
Hepatitis A; Indonesia; vaccination
Author: Randy Adiwinata, Andi
Kristanto, Timoteus Richard, Daniel Edbert, Frida Angelina, Eppy Eppy, Ifael Y
Mauleti, Soroy Lardo, Iman Firmansyah, Rika Bur, Titos Ahimsa, Erni J Nelwan
Journal Code: jpkedokterangg170237
