INVESTIGATION OF EFFECT OF ADDING HYDROPHOBICALLY MODIFIED WATER SOLUBLE POLYMERS ON THE STRUCTURE AND VISCOSITY OF ANIONIC VESICLE DISPERSION
ABSTRACT: This present study
was conducted to investigate the effect of adding hydrophobically modified
end-capped (HM) polymers with various polyethylene oxide (PEO) chain lengths on
the structure and viscosity of anionic vesicles dispersion. A pronounced
increase in viscosity was observed upon adding small amount of such polymers.
Based on the dynamic light scattering (DLS) and small angle neutron scattering
(SANS) analysis, 10 to 30 polymer molecules per vesicles can reach maximum
viscosity and where polymer molecules can interconnect the vesicles without
disrupting their structure. In addition, the kinetic stability of the vesicle
dispersion also enhanced. From the measurement of the electrical conductivity
of the dispersion, it was observed that the presence of the PEO and polypropylene
oxide (PPO) group could induce the permeability of the vesicle membrane by
altering their internal structure. Controlling viscosity of vesicles dispersion
without changing its structure is useful for the further application of
vesicles system such as in drug delivery, cosmetics and biomedical.
KEYWORDS: hydrophobically
modified polymers; viscosity; structure of vesicles; chain length of polymer
Author: Marco Sandjaja, Maria
Lucia Ardhani Dwi Lestari
Journal Code: jpkimiagg170031
