SINTESIS DAN KARAKTERISASI SELULOSA BAKTERI-SITRATKITOSAN SEBAGAI PEMBALUT LUKA ANTIMIKROBA
Abstract: Bacterial cellulose,
produced by Acetobacter xylinum, is an interesting material for using as a
wound dressing since it provides moist environment to a wound resulting in a
better wound healing. However, bacterial cellulose (BC) itself has no
antibacterial activity to prevent wound infection. To achieve antibacterial
activity, chitosan were impregnated into bacterial cellulose by cross linking
reaction using citric acid as cross linker. The thickness, water and saline
absorption capacity, water vapour transmission rate (WVTR), mechanical
properties and antibacterial activity of composite were investigated. The
result show an important increase in absorption capacity when BC was treated
with citric acid and chitosan and the maximum value was reached at 21.5 gig in
DM water and 8.2 gig in saline solution}. The WVTR analysis of all the test
membranes was found to be less than WVTR value of control without sample. The
result also showed that bacterial cellulose-citrate-chitosan (BC-AST) exhibited
antibacterial activity against E. coli, S. typhi, P. aeruginosa and S. aureus
Penulis: Farah Nurlidar, Lely
Hardiningsih, Darmawan Darwis
Kode Jurnal: jpkimiadd130793
