PROFIL KADAR MDA PADA TUMOR KULIT MENCIT (Mus musculus) SEBAGAI AKIBAT PEMBERIAN EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L) DAN EKSTRAK METANOL BENALU TEH (Scurulla atropurpurea Bl. Dancer)
Abstract: Malondialdehyde
(MDA) is widely used as an indicator of lipid peroxidation. Increased levels of
MDA have been associated with a variety of tumor diseases , one of is a skin
tumor. To cope with this disease use several medicinal plants which are leaves
of soursop (Annona muricata L) and tea parasite (Scurulla atropurpurea Bl.
dancer) . This study aims to determine the profile of MDA in mouse skin tumors
as a result of ethanol extract of leaves of soursop and methanol extract of tea
parasite. The sample used in this study were mouse skin tumors derived from
mice induced by using 7.12 - Dimethilbenz(α)Antrasen (DMBA) and ethanol extract
of leaves of soursop and methanol extract of tea parasite. While the
observation parameters are obtained via MDA spectrophotometer method. The
result of this research showed that the levels of MDA in mouse skin tumors
induced ethanol extract of leaves of soursop and methanol extract of tea
parasite is different. Lowest MDA levels (34.95nmol/g) contained in the DS3
that comes from DMBA-induced mice 25μg/100μl of acetone and ethanol extracts of
soursop leaf 60mg/kg
Penulis: Kholifah Holil
Kode Jurnal: jpbiologidd130795
