Pengaruh Pemberian Ekstrak Etanol Kelopak Bunga Rosella (Hibiscus sabdariffa, L) Terhadap Kadar LDL Pada Mencit Putih Betina
Abstract: Research on the
effect of roselle calyx ethanol extract (Hibiscus sabdariffa Linn) on the levels of LDL female white mice have been
done. The extract was administered orally with a variety doses 500, 700 and
1000 mg /kg bw once daily for 7, 14 and 21 days. as a negative control group using white
female mice were given standard diet, while the positive control were
given atherogenic cocktail as induction
. The results showed that the ethanol extract of roselle calyx apparently have
a significant effect on levels of LDL blood cholesterol of female white mice.
dose of 28 mg/20 g bw showed reduced blood levels of LDL cholesterol better
than a dose of 14 mg/20g bw and 19.6/20g
bw. Based on further test duncan, reduced levels of LDL cholesterol on day 21
showed excellent results compared to most day 7th and 14th.
Penulis: Surya Dharma, Erdinal,
Zet Rizal
Kode Jurnal: jpfarmasidd100077
