FORMULASI SEDIAAN MOUTHWASH DARI SARI BUAH SIRIH (Piper betle L.) VARIETAS SIRIBOAH
Abstrak: Piper betle fruit
empirically is believed to maintain oral
health, but unfortunately the use of piper betle fruit not to be proven
scientifically, therefore one of the efforts in explore benefits of betel fruit
is to formulatedinto mouthwash. The aim of this research was to prepared stable
and effective mouthwash preparation which is inhibit the growth of
Streptococcus mutans. There were 3 formula designed by varying the concentration of the piper
betle fruit juice 3, 4 and 5 % v/v respectively. Stability evalution carried
out before and after accelerated condition at 5oC and 35oC for 10 cycles in which the
parameter were organoleptic, pH value,
viscosity and inhibitory Streptococcus
mutans of the bacteria. The assay results of the inhibition of each formula
with agar diffusion method showed that the 3 formula were able to inhibit the
growth of Streptococcus mutans, but the most optimum stability and effective
inhibiting Streptococcus mutans was formula F3,that contain 5% fruit juice, due to there was no significant change before
and after accelerated condition.
Penulis: Ririn, Amran Ilyas
Tandjung, Sarif Wagola
Kode Jurnal: jpfarmasidd130269
