Efek Ekstrak Etanol Kulit Kayu Manis (Cinnamomum zeylanicum Blume) Terhadap Susunan Saraf Pusat Mencit Betina Putih
Abstract: Research on central
nervous system stimulant activity of the ethanol extract of Cinnamomum
zeylanicum Blume bark against female white mice with different levels of doses
have been done. Testing done by observing the immune system by using a rotary
road test, motor activity and sensory observations using automatic tool hole
board, and observation of sleep and long sleep induction. Phenobarbital 50 mg /
kg bw used as inducted . Preliminary trials showed that the ethanol extract of
Cinnamomum zeylanicum blume with a dose of 500 mg / kg bw had an effect on the
central nervous system. Whereas at the specific testing, the effect on the
central nervous looks at a dose of 250 mg / kg bw, which showed a statistically
significant difference compared with the control group of animals (P <0.05).
Penulis: Helmi Arifin, Leli
Sriyani, Zet Rizal
Kode Jurnal: jpfarmasidd100086
