KADAR RADIKAL SUPEROKSID (O2-), NITRIC OXIDE (NO) DAN ASUPAN LEMAK PADA PASIEN HIPERTENSI DAN TIDAK HIPERTENSI
ABSTRACT: Hypertension closely
related to impaired endothelial dependent vasodilation due to a decline in
theavailability of nitric oksid (NO) and high fat intake, decreased Nitric
Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the
differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and
fat intake inpatients with hypertension and not hypertension .Methods: this
research is cross sectional, research amount sampelnya taken at random. 24
respondent patientsconsisting of 12 cases control, and 12 the age of 65 40-
tahun.pengambilan samples conducted in outpatient installationregional general
hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat
intake.Results: the average rate of Superoksid respondents not hypertension
0.250± 0, 034U/mL, 0,314± 056U/mLhypertension, Average levels of Nitric oksid
respondents not hypertension 116,083± 46,962μ M, of which hypertension72,333±
40,51μ M, average consumption of fat respondents not hypertension 41,65± 8,
32gram, 51,52± 6,74gramhypertension . Based on the test results the difference
against Superoksid levels of both research groups using a t-testtwo samples are
free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the
value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p =
0,004) which means that there is a meaningful difference in the levels
ofSuperoksid, Nitric oxide and the level of fat intake among respondents with
no hypertension and hypertension.Conclusion: there is a radical difference in
the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients
withhypertension and not hypertension.
Penulis: Pudji Astutik,
Merryana Adriani, Bambang Wirjatmadi
Kode Jurnal: jpkesmasdd140413