POTENSI AFRODISIAK KANDUNGAN AKTIF BUAH CABE JAWA (Piper retrofractum Vahl) PADA TIKUS JANTAN GALUR WISTAR
Abstract: Java long pepper
(Piper retrofractum Vahl) is one of the Indonesian original plants having
aphrodisiac activity. This study was aimed to isolate piperine and to evaluate
aphrodisiac potency of piperine and piperine-free insoluble n-hexane fraction
from ethanolic extract of P. retrofractum. Twenty five male rats were
randomized into 5 groups. Oral repeated administration once a day for 27 days
were given to andriol group (0.72 mg/day), CMC-Na 1%, piperine (1.6 mg/kg body
weight), piperine-free insoluble n-hexane fraction (2.1 mg/kg body weight),
insoluble n-hexane fraction (31.72 mg/kg body weight). Rat’s sexual behavior
including sexual introduction and climbing were observed in day 0, 1, 3, 5, 7,
11, 15, 19, 23, and 27. Normal and homogenous data were analyzed statistically
with one-way ANOVA, followed by LSD test. The result showed that the
administration of andriol, piperine, piperine-free insoluble n-hexane fraction,
and total insoluble n-hexane fraction has a significant increase in the
frequency of introduction, compared to the group of CMC-Na 1% (p<0.05).
There was also a significant increase of piperine and piperine-free insoluble
n-hexane fraction in the frequency of climbing (p<0.05).
Penulis: Siti Muslichah
Kode Jurnal: jppertaniandd110225
