Pengaruh Pemberian Ekstrak Etanol Daun Kecapi (Sandoricum koetjape (Burm.f.) Merr.) Terhadap Penurunan Kadar Kolesterol Total pada Mencit Jantan (Mus musculus)
Abstrak: The research about
utilization of ethanol extract form leafkecapi (Sandoricum koetjape
(Burm.f.)Merr.)has been done, it proved could decrease total cholesterol levels in male mice (Mus
musculus). In this research sample macerated with ethanol 96% and then
concentrated by rotary evaporator, and gained 15.6% of yield. Based on the
results of phytochemical test, secondary metabolites compound that contained in
bark kecapi are alkaloid, flavonoid, triterpenoid, steroid, phenolic and
saponin. On antihiperkolesterolemia activity test by using male mice, there are
several treatments that negative control (-), positive control (+) and three
treatment with different doses i.e. a low doses (9.5 mg/kg BB), middle doses
(19 mg/kg BB) and high doses (38 mg/kg BB). The parameter measured was blood
serum of male mice by using a Cholesterol Test Strips. From this test it showed
that the effectiveness of decreased total cholesterol level doses of 19 mg/kg
BB showed total cholesterol level under 100 mg/dL.
Keywords: Leaf kecapi
(Sandoricum koetjape (Burm.f.) Merr.), Phytochemicals test, Total cholesterol
levels, Cholesterol test strips
Penulis: Rudi Kartika
Kode Jurnal: jpkimiadd160026
