Biopreparasi Lendir Bekicot (Achatina fulica) Menggunakan Membran Kitosan sebagai Kasa Pembalut untuk Penyembuhan Luka
Abstract: The aim of this research purposes is
biopreparation snail slime on chitosan membrane as a gauze bandage for wound
healing in vivo. Snail slime contains substances are achatin isolates, heparan
sulfate, and calcium. The content
of isolates achatin
useful as an
antibacterial and anti-inflamation, while
calcium plays a
role in hemostasis. Chitosan has
uses in the field of biomedical and pharmaceutical, among others, chitosan
fibers as threads in surgery that can be
absorbed by the human body; bandage covering the wound and the carrier medicine.
Chitosan are biodegradable, degradable,
non-toxic, non-immunogenic to the body tissue of animals. Wound healing is very
important to restore the integrity of the skin as soon as possible and is a
complex and dynamic process. Phase involving fibroblast cell proliferation is
one important step in wound healing. Wound healing with snail slime and
chitosan may be an alternative because it has many benefits. Research methods include synthezise non
biomembran chitosan glycerol, snail slime isolation, treatment stage in test
animals 5 mice are negative
control group; snail
slime treatment; chitosan
membrane; snail slime
and chitosan membrane ratio of 1:
1; and a positive control. The results showed synergistic effect of antibacterial and anfiinflamation snail slime and chitosan is able to accelerate the proliferative phase of
wound healing process. Bioprepration snail slime is integrated in biomembran
chitosan can be applied as gauze wound dressing that is safe and effective in
order to accelerate the wound healing process
Penulis: Agnes Sri Harti,
Atiek Murharyati, S. Dwi Sulisetyawati
Kode Jurnal: jpbiologidd150320
