THE EFFECT OF VIRGIN COCONUT OIL ON LYMPHOCYTE AND CD4 IN CHICKEN VACCINATED AGAINST Avian Influenza VIRUS
Abstract: This research aimed
to find preventing alternative of avian influenza (AI) disease in broiler
chickenby increasing body immune. Lymphocyte T would directly react to antigen
presented to the cell surfaceby antigen presenting cell (APC). Th-CD4
interaction functioned to maintain Th-APC bond intactduring specific antigen
activation. Fatty acid in virgin coconut oil (VCO) was potential
asimmunostimulant, which therefore could increase chicken immunity through the
increase of lymphocyteT and Th-CD4. This research used 40 one-day-old broiler
chickens. The method applied was CompletelyRandomized Factorial Design in which
the first factor was two levels of vaccine, namely groups of AIvaccinated and
unvaccinated. The second factor was four levels of VCO namely 0, 5, 10, 15
mL/kg feed.Day Old Chick (DOC) were divided into eight treatment groups and
repeated five times. Feed and waterwere given ad libitum for four weeks. The
result showed that the number of lymphocyte and Th-CD4 inchickens given 10 mL
per kg feed and vaccinated with AI was higher than that in chickens given
VCOwithout AI vaccine.
Author: E.Y.W. Yuniwarti, W.
Asmara, W.T. Artama, C.R. Tabbu
Journal Code: jppeternakangg120083
