Balanokarpol dan Ampelopsin H, Dua Oligoresveratrol dari Kulit Batang Hopea odorata (Dipterocarpaceae)
ABSTRACT: Two
oligoresveratrol, namely balanocarpol (2) and ampelopsin H (3) had been
isolated from the steam bark of Hopea odorata (Dipterocarpaceae). The
structures of these compounds were elucidated based on physical and
spectroscopic data (MS, 1H and 13C NMR 1D and 2D). The activity of these
compounds was evaluated against the 2-deoxyribose degradation induced by the
hydroxyl radical generated via a Fenton-type reaction. The result showed that
activity each compounds as radical hydroxyl scavenger of balanocarpol, and
ampelopsin H with an IC50 1802.3 and 4840.0 μg/mL, respectively. Each compound
showed low activity. Vitamin C (IC50 83.9 μg/mL) and butylated hydroxyl toluene
(1328.0 μg/mL) were used as positif controls. These results suggest that
oligoresveratrols from stem bark of H. odorata may be useful as potential
sources of natural antioxidants.
Penulis: Sri Atun, Nurfina
Aznam, Retno Arianingrum, Masatake Niwa
Kode Jurnal: jpkimiadd060078
