UJI ANTIINFLAMASI INFUSA BUNGA SEROJA (NELUMBO NUCIFERA GAERTN) PADA STRUKTUR MIKROANATOMI GINJAL MENCIT (MUS MUSCULUS) YANG MENGALAMI STRES
ABSTRACT: Lotus (Nelumbo
nucifera Gaertn) is an aquatic plant that contains various kinds of
phytocemical compounds, one of which is quercetin that has the potentiality to
suppress inflammation. The arm of this research was to observe the
anti-inflamation effect of Lotus infused water on kidneys mikroanatomical
structure of mice (Mus musculus). The test subjects used in this research were
2 months old male swiss strain mice. This research utilized the completely
randomized design (CRD) with 5 treatments and 3 replication each. The
treatments groups were the given Lotus infused water orally consist of 5,6 mg/g
BW, 8,4 mg/g BW and 11,2 mg/g BW dosages for 7 days, the normal control groups
and the negatif control groups. Kidney microanatomical preparations were made
using paraffin method with HE coloring. The result of this research show this
research shows that stressing the mice may affect their kidneys microanatomical
structure in forms of cell swelling (edema), hidropic degenerations, necrosis,
and atrophy. The consumtions of Lotus infused water can suppress the
inflammation on kidneys mikroanatomical structure of mice. The changes on
kidneys tubulus and glomerolus of mice may start to be visible on the
consumtion of 5,6 mg/g BW dosage of infused water.
Penulis: Yuniarti, Diah
Wulandari Rousdy, Rahmawati
Kode Jurnal: jpbiologidd150123
