TES INHIBISI PADA DAUN SIRIH MERAH (Piper crocatum) TERHADAP Staphylococcus aureus DAN Salmonella typhi

Abstract: The  red  betel  leaves  (Piper  crocatum)  has  many  benefits  such  as  antioksidant,  antidiabetic,  antineoplastic, antiseptic,  and  antiinflammation.  This  research  aims  to  investigate  the  antibacteial  activity  on  red  betel  leaves againsts  Staphylococcus  aureus  and  Salmonella  typhi  with  determine  the  red  betel  leaves  extract  minimum  resist concentrate  which  capable  to  inhibit  the  growth  of  bacteria.  This  research  was  held  on  October  2014  at Microbiological  Laboratory  of  Lampung  University  Medical  Faculty.  The  red  betel  leaves  extract  obtained  from Organic  Chemical  Laboratory  of  Lampung  University  with  maceration  technique.  The  sirih  merah  leaves  activity performed with in vitro particularly with Kirby bauer method which is done by making the well. The results of this research presented that all concentration of red betel leaves such 3,125%, 6,25%, 12,5%, 25%, 50% and 100%, has antibacterial  activity  towards  Staphylococcus  aureus  and  Salmonella  typhi  bactery,  with  the  highest  inhibitory concentration  at 100% that is 16,3 mm on Staphylococcus aureus and 12 mm on Salmonella typhi. Conclusion is red betel leaves inhibit the growth of positive gram bacteria stronger than the negative gram bacteria. 
Kata Kunci: Piper crocatum, Staphylococcus aureus, Salmonella typhi
Penulis: Soleha TU, Carolia N, Kurniawan SW
Kode Jurnal: jpkedokterandd150166

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