Kandungan Kimia dan Aktivitas Sitotoksik Ekstrak dan Fraksi Herba Anting-anting terhadap Sel Kanker Payudara MCF-7
Abstract: Acalupha indica,
belongs to Euphorbiaceae family, is annual herb which distributed widely in
Asia, including Indonesia. Extract and fraction of Acalypha indica were sreened
for phytochemical constituents and investigated for its cytotoxicity against
human breast cancer MCF-7 using MTT assay. Ethanolic extract of A.indica showed
cytotoxicity against MCF-7 with an IC50 225 μg/ml. While for the fraction,
ethyl acetate fraction showed best cytotoxicity compared to n-hexane and water
fraction with an IC50 387 μg/ml. Phytochemical screening to the ethyl acetate
fraction showed that the fraction contain flavonoids, polyphenols, monoterpenes
and sesquiterpenes, triterpenoids, and quinones.
Penulis: Maya Febriyanti, Supriyatna, Rizky Abdulah
Kode Jurnal: jpfarmasidd140110
