Efek Glycine max Varietas Anjasmoro terhadap Kadar Timbal dan Malondialdehid pada Mencit Terintoksikasi Timbal
Abstract: The objective of
this research is investigating the effect of Glycine max Anjasmoro variety to
mice with lead intoxication by measuring the levels of Pb in mice's (Mus
musculus) blood and MDA in mice's liver and kidney strain BALB/C by using the
thiobarbituric acid reactive substance (TBARS) assay. Research carried out by
using 20 mice strain BALB/C that were randomly divided into four groups of five
mice including negative control, positive control, treatment, and reference.
All groups except positive control were intoxicated with lead in a dose of 25
mg/kg body weight for the duration of seven days. One gram of Glycine max has
been given to the treatment group and positive control. There after 64 mg/kg
body weight of vitamin has been given to the reference group. The results
showed that Glycine max Anjasmoro varieties was significantly decrease the
levels of lead in mice's blood and also reduce the levels of MDA in the liver
and kidney although the results were not significant.
Penulis: Rika Yulia, Lidya
Karina, Veronica, Juliana Christyaningsih
Kode Jurnal: jpfarmasidd140112
